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Computational Cancer Biology
Program
Algorithmic Challenges in Genomics
Location
Calvin Lab Auditorium
Date
Monday, Feb. 1
–
Friday, Feb. 5, 2016
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Click on the titles of individual talks for abstract, slides and archived video.
Monday, Feb. 1, 2016
8:45
–
9:05 a.m.
Coffee & Check-In
9:05
–
9:15 a.m.
Opening Remarks
9:15
–
9:45 a.m.
The Current State of Mutation Detection and Prospects for Long Read Sequencing
Jared Simpson (Ontario Institute for Cancer Research)
9:45
–
10:15 a.m.
Modeling Cancer Evolution from Genomic Data
Niko Beerenwinkel (ETH Zürich)
10:15
–
11 a.m.
Break
11
–
11:30 a.m.
Interaction-based Methods for Uncovering Genes Functionally Important in Cancers
Mona Singh (Princeton University)
11:30 a.m.
–
12 p.m.
Joint Analysis of Multiple Cancer Types for Revealing Disease-Specific Genomic Events
Ron Shamir (Tel Aviv University) & David Amar (Tel Aviv University)
12
–
2 p.m.
Lunch
2
–
2:30 p.m.
Somatic Mutations that Alter RNA Splicing in Human Cancers
Angela Brooks (UC Santa Cruz)
2:30
–
3 p.m.
Algorithms for Population Genomics and Cancer Genomics
Serafim Batzoglou (Stanford University)
3
–
3:30 p.m.
Break
3:30
–
4 p.m.
Mechanisms of Amplification in Tumor Genomes
Vineet Bafna (UC San Diego)
4
–
5 p.m.
Afternoon Discussion
5
–
6 p.m.
Reception
Tuesday, Feb. 2, 2016
8:30
–
9 a.m.
Coffee & Check-In
9 a.m.
–
9:30 p.m.
Challenges and Opportunities in Intelligent Molecular Medicine
Igor Jurisica (University of Toronto)
9:30
–
9:45 a.m.
Fast and Scalable Inference of Cancer Cell Lineages Using Multi-sample Deep Sequencing Somatic SNVs
Victoria Popic (Stanford University)
9:45
–
10:15 a.m.
Molecular Data Integration for Precision Medicine in Breast Cancer
Laura Van 'T Veer (UCSF)
10:15
–
11 a.m.
Break
11
–
11:40 a.m.
Molecular Characterization for Diagnoses and Treatment
David Haussler (UC Santa Cruz)
11:40
–
11:55 a.m.
CoMEt: A Statistical Approach to Identify Combinations of Mutually Exclusive Alterations in Cancer
Max Leiserson, Brown University
12
–
2 p.m.
Lunch
2
–
2:30 p.m.
Finding Mutated Subnetworks Associated with Survival in Cancer
Fabio Vandin (University of Padova)
2:30
–
3 p.m.
Diverse High Throughput Technologies in Cancer Research and Synthetic Biology
Zohar Yakhini (Agilent Technologies and Technion)
3
–
3:30 p.m.
Break
3:30
–
3:45 p.m.
The Copy Number Transformation Problem
Meirav Zehavi (Technion Israel Institute of Technology)
3:45
–
4 p.m.
Inferring Selective Advantage Relationships to Reconstruct Cancer Progression Models
Marco Antoniotti (Università degli Studi di Milano Bicocca)
4
–
5 p.m.
Afternoon Discussion
Wednesday, Feb. 3, 2016
8:30
–
9 a.m.
Coffee & Check-In
9
–
9:30 a.m.
Toward Pathway-and Pancancer-Guided Interpretation of an Individual’s Cancer Genome
Josh Stuart (UC Santa Cruz)
9:30
–
9:45 a.m.
Somatic Structural Variation Discovery in Multiple Cancer Genomes
Iman Hajirasouliha (Stanford University)
9:45
–
10:15 a.m.
Towards Inference of Fitness Landscapes in Human Cancer
Sohrab Shah (BC Cancer Research Agency)
10:15
–
11 a.m.
Break
11
–
11:40 a.m.
Tumor Evolution - Simplicity and Constraints
Paul Spellman (Oregon Health and Science University)
11:40
–
11:55 a.m.
Inference of Personalized Drug Targets via Network Propagation
Dana Silverbush (Tel Aviv University)
12
–
2 p.m.
Lunch
2
–
2:30 p.m.
Quantifying the Evolutionary Dynamics of Human Tumor Growth and Progression
Christina Curtis (Stanford University)
2:30
–
3 p.m.
Complexity Issues in Rearrangement Evolution
Chris Greenman (University of East Anglia)
3
–
3:30 p.m.
Break
3:30
–
4 p.m.
Inferring Evolution by Copy Number Variations in Tumor Cell Populations
Russell Schwartz (Carnegie Mellon University)
4
–
5 p.m.
Afternoon Discussion
Thursday, Feb. 4, 2016
8:30
–
9 a.m.
Coffee & Check-In
9
–
9:30 a.m.
Interpreting Cancer Genomes with Network Knowledge
Trey Ideker (UC San Diego)
9:30
–
9:45 a.m.
Multi-State Perfect Phylogeny Mixture Deconvolution and Applications to Cancer Sequencing
Mohammed El Kebir, Brown University
9:45
–
10:15 a.m.
Optimizing Combination Cancer Therapy Based on Single Cell Analysis
Sylvia Plevritis (Stanford University)
10:15
–
11 a.m.
Break
11
–
11:40 a.m.
Synthetic Rescue Determinants of Resistance and Response to Cancer Therapy
Eytan Ruppin (University of Maryland)
11:40
–
11:55 a.m.
Survival Time Prediction from Mutation Profiles Using Gene Networks
Marine Le Morvan (Mines ParisTech)
12
–
2 p.m.
Lunch
2
–
2:30 p.m.
Modeling Mutational Patterns in Tumor Genomic Data
Ewa Szczurek (ETH Zürich)
2:30
–
3 p.m.
Insights To Treatment Resistance and Precision Therapy In Prostate Cancer
Colin Collins (Vancouver Prostate Center)
3
–
3:30 p.m.
Break
3:30
–
4 p.m.
Mutual Exclusivity of Mutations Across Different Cancer Types - A Molecular Network Perspective
Teresa Przytycka (National Institutes of Health)
4
–
5 p.m.
Afternoon Discussion
Friday, Feb. 5, 2016
8:30
–
9 a.m.
Coffee & Check-In
9
–
9:30 a.m.
Detection and Systems Level Identification of Expressed, Clone Specific Structural Alterations that Drive the Tumor Phenotype
Cenk Sahinalp (Indiana University)
9:30
–
9:45 a.m.
BitPhylogeny: A Probabilistic Framework for Reconstructing Intra-tumor Phylogenies
Thomas Sakoparnig (University of Basel, Biozentrum)
9:45
–
10:15 a.m.
Expression Analysis of Tumors Based on Patterns in Alternative Splicing
Elizabeth Purdom, UC Berkeley
10:15
–
11 a.m.
Break
11
–
11:30 a.m.
Modeling the Impact of Somatic Alterations in Human Cancers
Hatice Ulku Osmanbeyoglu, Memorial Sloan Kettering Cancer Center
11:30 a.m.
–
12 p.m.
Rank-Based Representations to Learn from Omics Data
Jean-Philippe Vert (MINES ParisTech)
12
–
12:15 p.m.
Closing Discussion
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