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From Algorithms to Discovery in Genome-Scale Biology and Medicine
Program
Computational Innovation and Data-Driven Biology
Location
Calvin Lab Auditorium
Date
Tuesday, July 5
–
Friday, July 8, 2022
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The Workshop
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All talks are in Pacific Time. Schedule subject to change.
Tuesday, July 5, 2022
12:45
–
1:15 p.m.
Coffee & Check-In
12:55
–
1 p.m.
Session 1: Gene Regulation
1:15
–
1:30 p.m.
Opening Remarks
1:30
–
2 p.m.
BANKSY: A Spatial Omics Algorithm that Unifies Cell Type Clustering and Tissue Domain Segmentation
Shyam Prabhakar (Genome Institute of Singapore)
2
–
2:30 p.m.
Break
2:30
–
3 p.m.
Spatial Transcriptomics Identifies Neighbourhoods and Molecular Markers of Alveolar Damage in the Lung for COVID-19 Patients
Martin Hemberg (Brigham and Women's Hospital)
3
–
3:30 p.m.
Landscapes of Human cis-regulatory Elements and Transcription Factor Binding Sites Evolutionarily Constrained in the Mammalian Lineage
Zhiping Weng (UMass Chan Medical School)
3:30
–
5 p.m.
Reception & Poster Session
Wednesday, July 6, 2022
9
–
9:30 a.m.
Coffee & Check-In
9:25
–
9:30 a.m.
Session 2: Systems Medicine
9:30
–
10 a.m.
Formatting Biological Big Data to Enable (Personalized) Systems Pharmacology
Patrick Aloy (Institute for Research in Biomedicine)
10
–
10:30 a.m.
TBD
Jimmie Ye (UCSF)
10:30
–
11 a.m.
Break
11
–
11:30 a.m.
Genomics of Cancer
Noam Shomron (TAU)
11:30 a.m.
–
12 p.m.
Understanding Molecular Complexity for Precision Medicine
Natasa Przulj (ICREA; Barcelona Supercomputing Center; University College Londo…
12
–
2 p.m.
Lunch
1:55
–
2 p.m.
Session 3: Machine Learning
2
–
2:30 p.m.
Machine Learning for Single-Cell 3D Epigenomics
Jian Ma (Carnegie Mellon University)
2:30
–
3 p.m.
A Statistical, Reference-Free Algorithm Subsumes Myriad Problems in Genome Science
Julia Salzman (Stanford)
3
–
3:30 p.m.
Break
3:30
–
4 p.m.
Using Large-Scale Clinico-Genomics Data for in silico Clinical Trials and Precision Oncology
James Zou (Stanford University)
4
–
5:30 p.m.
Future Directions in Genomic Discovery
Roded Sharan (TAU)
,
Nadav Ahituv (UCSF)
Thursday, July 7, 2022
9
–
9:30 a.m.
Coffee & Check-In
9:25
–
9:30 a.m.
Session 4: Network Biology
9:30
–
10 a.m.
Interactome Networks in Genetic and Infectious Diseases
Pascal Falter-Braun (Institute of Network Biology - Helmholtz Zentrum Munich)
10
–
10:30 a.m.
Long-Range Propagation of Genetic Effects in Molecular Networks
Andreas Beyer (CECAD, University of Cologne, Germany)
10:30
–
11 a.m.
Break
11
–
11:30 a.m.
A Binary Quantitative Interaction Mapping Approach: Elucidating Multiprotein Complexes in Health and Disease
Erich Wanker (Max Delbrueck Center for Molecular Medicine)
11:30 a.m.
–
12 p.m.
A Tyrosine Kinase Protein Interaction Map Reveals Targetable EGFR Network Oncogenesis in Lung Cancer
Sourav Bandyopadhyay (UCSF)
12
–
2 p.m.
Lunch
2
–
2:30 p.m.
Computational Approaches to Study Interactions Between Mutagenic Processes and Cellular Processes
Teresa Przytycka (National Center for Biotechnology Information)
2:30
–
3 p.m.
Mapping Biological Pathways Using Systematic Genetics and Cell Biology
Brenda Andrews (University of Toronto)
3
–
3:30 p.m.
Coffee & Ride
3:30
–
5:30 p.m.
Hike in Strawberry Canyon
Friday, July 8, 2022
9
–
9:30 a.m.
Coffee & Check-In
9:25
–
9:30 a.m.
Session 5: From Genotype to Phenotype
9:30
–
10 a.m.
Algorithms for Inferring Phenotypes from Ancient DNA
Tony Capra (UCSF)
10
–
10:30 a.m.
Predicting the Deleteriousness of Genomic Variants – Big and Small
Martin Kircher (BIH @ Charité / University of Luebeck)
10:30
–
11 a.m.
Break
11
–
11:30 a.m.
How Genome 3D Organization Regulates Alternative Splicing?
Gil Ast (Tel Aviv University)
11:30 a.m.
–
12 p.m.
Determining the Molecular Intermediates Between Genotype and Phenotype
David Knowles (Columbia University/New York Genome Center)
12
–
12:30 p.m.
Distinct Gene Programs Underpinning ‘Disease Tolerance’ and ‘Resistance’ Against Infections
Irit Gat-Viks (Tel Aviv University)
12:30
–
12:45 p.m.
Closing Remarks
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