Spring 2014

Crowd-sourcing Genetic Discovery

Friday, Feb. 21, 2014 3:30 pm4:15 pm

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Calvin Lab Auditorium

Over the past 6 years, over a half-million people have joined 23andMe to learn about their genetics. Most of these people in turn contribute phenotype data to our research efforts. This dataset includes tens of thousands of trios as well as thousands of phenotypes. I'll survey some of the things we've learned, including: how to improve short (2-4cM) IBD segment detection; the admixed ancestry of individuals in the US, detecting local ancestry, the heritability of a wide range of traits, and hundreds of new genetic associations for some interesting conditions (infectious diseases, sleep habits, food preferences, morphology, and more).