Spring 2018

Precise Multimodal Control of Neural Ensemble Activity

Wednesday, Feb. 14, 2018 2:00 pm2:30 pm

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Calvin Lab Auditorium

I will present a new method to control the activity of neural ensembles in the intact brain with holographic multiphoton optogenetics. We combined 3D light sculpting with newly engineering microbial opsins, to permit the cellular resolution, millisecond timing control of user-defined subsets of neurons in the awake mouse brain. This experimental approach should allow researchers to test fundamental theories of neural computation and coding in the brain.